Is NEUPOGEN® right for me?

If you are on a strong chemotherapy, it's important to ask your doctor if you are at risk for developing febrile neutropenia (neutropenia with fever), and how NEUPOGEN® helps reduce that risk. Talk to your doctor about other factors that may put you at additional risk.

Start the discussion with your doctor by viewing these questions

Questions to ask your doctor

It's important to have a discussion with your doctor about your white blood cell counts, the risk of infection, and how NEUPOGEN® could help.

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Important Safety Information

Who should not take NEUPOGEN®?
Do not take NEUPOGEN® if you have had an allergic reaction to human G‐CSFs such as NEUPOGEN® (filgrastim) or Neulasta® (pegfilgrastim) or other forms of filgrastim.

What should I tell my doctor before taking NEUPOGEN®? Before you take NEUPOGEN®, tell your doctor if you:

  • have a sickle cell disorder
  • have a problem with your kidneys, as you may need more frequent urine tests
  • are allergic to latex
  • are pregnant, or plan to become pregnant. It is not known if NEUPOGEN® will harm your unborn baby.
  • are breastfeeding, or plan to breastfeed. It is not known if NEUPOGEN® passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How will I receive NEUPOGEN®?

  • If you or your child are receiving NEUPOGEN® because you or your child are also receiving chemotherapy, the last dose of NEUPOGEN® should be injected at least 24 hours before your next dose of chemotherapy.

What are possible serious side effects of NEUPOGEN®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking NEUPOGEN®. A ruptured spleen can cause death. Call your doctor right away if you or your child has pain in the left upper stomach area or left shoulder.
  • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your doctor or get emergency medical help right away if you or your child has shortness of breath with or without a fever, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. NEUPOGEN® can cause serious allergic reactions. These reactions can cause a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, and sweating. If you or your child starts to have any of these symptoms, stop using NEUPOGEN®, and call your doctor or get emergency help right away. If you or your child have an allergic reaction during the injection of NEUPOGEN®, stop the injection right away.
  • Sickle Cell Crises. You may have a serious sickle cell crisis if you have a sickle cell disorder and take NEUPOGEN®. Serious and sometimes fatal sickle cell crises can occur in patients with sickle cell disorders receiving filgrastim. Call your doctor right away if you have symptoms of sickle cell crisis such as pain or difficulty breathing.
  • Kidney injury (glomerulonephritis). Kidney injury has been seen in patients who received NEUPOGEN®. Call your doctor right away if you experience puffiness in your face or ankles, blood in your urine or brown colored urine or you notice you urinate less than usual.
  • Capillary Leak Syndrome. NEUPOGEN® can cause fluid to leak from blood vessels into your body's tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
    • swelling or puffiness and are urinating less often
    • trouble breathing
    • swelling of your stomach-area and feeling of fullness
    • dizziness or feeling faint
    • a general feeling of tiredness
  • Decreased platelet count (thrombocytopenia). Your doctor will check your blood during treatment with NEUPOGEN®. Tell your doctor if you have unusual bleeding or bruising while taking NEUPOGEN®. This could mean a decrease of platelets, which reduces the ability of blood to clot.
  • Increased white blood cell count (leukocytosis). Your doctor will check your blood during treatment with NEUPOGEN®.
  • Inflammation of your blood vessels (cutaneous vasculitis). Tell your doctor if you develop purple spots or redness of your skin.

The most common side effects of NEUPOGEN® include aching in the bones and muscles. Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effect of NEUPOGEN®. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-332-1088.

Please see the NEUPOGEN® Patient Information for additional information.

The last dose of NEUPOGEN® (filgrastim) should be injected at least 24 hours before your next dose of chemotherapy. NEUPOGEN® should be injected at the same time each day. If you miss a dose, contact your doctor or nurse.

You must always use the correct dose of NEUPOGEN®. Too little may not protect you against infections, and too much may cause too many neutrophils to be in your blood. If you are giving someone else NEUPOGEN® injections, it is important that you know how to inject, how much to inject, and how often to inject.

For more information, please see the NEUPOGEN® Patient Product Information and talk to your doctor.

No use NEUPOGEN® durante las 24 horas anteriores ni las 24 horas posteriores a la administración de quimioterapia fuerte. NEUPOGEN® debe inyectarse a la misma hora todos los días. Si se salta una dosis, póngase en contacto con el médico o el enfermero.

Es indispensable que use siempre la dosis correcta de NEUPOGEN®. Una cantidad insuficiente quizás no ayude a reducir el riesgo de contraer infecciones, y un exceso podría generar demasiados neutrófilos en la sangre. Si usted le administra las inyecciones de NEUPOGEN® a otra persona, es importante que sepa cómo inyectar el medicamento, las dosis que debe inyectar y con qué frecuencia debe poner las inyecciones.

Para obtener más información sobre cómo preparar y administrar una inyección de NEUPOGEN® consulte la información del producto para los pacientes y la información de prescripción de NEUPOGEN®. Si tiene preguntas, deberá hablar con su médico.